The antibiofilm effect and mechanism of silver nanowire-modified glass ionomer cement against multi-species oral biofilm.

ABSTRACT:

Background

To investigate the antibiofilm effect and mechanism of the silver nanowire (AgNW)-modified glass ionomer cement (GIC) against multi-species oral biofilm, and to examine the mechanical and biochemical properties of this novel GIC material.

Methods

Conventional GIC was incorporated with different concentrations of AgNW and silver nanoparticles (AgNP). Multi-species biofilms of Streptococcus mutans, Streptococcus sobrinus, Lactobacillus fermentum, and Lactobacillus rhamnosus were cultured for 72 h on GIC specimens. Scanning electron microscopy (SEM) was adopted to examine the accumulation of biofilm on GIC surfaces. A live/dead assay was performed to assess the viability of bacteria. Extracellular polysaccharides (EPS) were labelled with Alexa Fluor 647-labelled dext

SUBMITTER: Guo T 

PROVIDER: S-EPMC11780787 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature