Fetal cardiac function in pregnancy affected by congenital heart disease: protocol for a multicentre prospective cohort study.

ABSTRACT:

Background

Congenital heart disease (CHD) is the most common fetal malformation, and it can result first in cardiac remodeling and dysfunction and later in cardiac failure and hydrops. A limited number of studies have evaluated cardiac function in fetuses affected by CHD. Functional parameters could potentially identify fetuses at risk of cardiac failure before its development. However, these techniques have not translated from research to clinical settings, due to a lack of standardization and poor repeatability. We seek to evaluate whether application of automated techniques to a cohort with fetal pathology could overcome these factors.

Methods

A multicenter cohort study will be carried out in eight teaching hospitals across Europe, Australia, and Middle East. Based on a p

SUBMITTER: Erenbourg A 

PROVIDER: S-EPMC11780818 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature