Performance and validation of a digital memory test across the Alzheimer's disease continuum.

ABSTRACT: Digital cognitive testing using online platforms has emerged as a potentially transformative tool in clinical neuroscience. In theory, it could provide a powerful means of screening for and tracking cognitive performance in people at risk of developing conditions such as Alzheimer's disease. Here we investigate whether digital metrics derived from an in-person administered, tablet-based short-term memory task-the 'What was where?' Oxford Memory Task-were able to clinically stratify patients at different points within the Alzheimer's disease continuum and to track disease progression over time. Performance of these metrics compared to traditional neuropsychological pen-and-paper screening tests of cognition was also analysed. A total of 325 people participated in this study: 49 patients wit

SUBMITTER: Toniolo S 

PROVIDER: S-EPMC11780857 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature