Hydrogel inspired by "adobe" with antibacterial and antioxidant properties for diabetic wound healing.

ABSTRACT: With the aging population, the incidence of diabetes is increasing. Diabetes often leads to restricted neovascularization, antibiotic-resistant bacterial infections, reduced wound perfusion, and elevated reactive oxygen species, resulting in impaired microenvironments and prolonged wound healing. Hydrogels are important tissue engineering materials for wound healing, known for their high water content and good biocompatibility. However, most hydrogels suffer from poor mechanical properties and difficulty in achieving sustained drug release, hindering their clinical application. Inspired by the incorporation of fibers to enhance the mechanical properties of "adobe," core-shell fibers were introduced into the hydrogel. This not only improves the mechanical strength of the hydrogel but also e

SUBMITTER: Li Z 

PROVIDER: S-EPMC11780960 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature