Robotic Microcapsule Assemblies with Adaptive Mobility for Targeted Treatment of Rugged Biological Microenvironments.

ABSTRACT: Microrobots are poised to transform biomedicine by enabling precise, noninvasive procedures. However, current magnetic microrobots, composed of solid monolithic particles, present fundamental challenges in engineering intersubunit interactions, limiting their collective effectiveness in navigating irregular biological terrains and confined spaces. To address this, we design hierarchically assembled microrobots with multiaxis mobility and collective adaptability by engineering the potential magnetic interaction energy between subunits to create stable, self-reconfigurable structures capable of carrying and protecting cargo internally. Using double emulsion templates and magnetic control techniques, we confine 10 nm iron oxide and 15 nm silica nanoparticles within the shell of 100 μm microca

SUBMITTER: Tran HH 

PROVIDER: S-EPMC11781029 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature