Cardiometabolic index as a predictor of gallstone incidence in U.S. adults: insights from NHANES 2017-2020.

ABSTRACT:

Background

Gallstone disease (GSD) is associated with obesity. The Cardiometabolic Index (CMI), a metric that accurately assesses central adiposity and visceral fat, has not been extensively studied in relation to GSD risk. This study investigates the link between CMI and GSD incidence in U.S. adults.

Methods

This study utilized data from the National Health and Nutrition Examination Survey(NHANES)(2017-2020) to assess the association between CMI and GSD, adjusting for confounders such as age, sex, race, chronic diseases, and lifestyle factors. Multivariable logistic regression models and subgroup analyses were employed. Generalized Additive Models (GAM) and advanced curve fitting techniques were used to explore potential non-linear relationships, with threshold effects dete

SUBMITTER: Li J 

PROVIDER: S-EPMC11781038 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature