Parsimonious versus extensive bleeding score: can we simplify risk stratification after percutaneous coronary intervention and reduce bleeding events by de-escalation of the antiplatelet strategy?

ABSTRACT:

Background and aims

Due to the multitude of risk factors outlined in the guidelines, personalised dual antiplatelet therapy (DAPT) guidance after percutaneous coronary intervention (PCI) is complex. A simplified method was created to facilitate the use of risk stratification. We aimed to compare the predictive and prognostic value of the 'Zuidoost Nederland Hart Registratie' (ZON-HR) classification for bleeding risk with the PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent DAPT (PRECISE-DAPT) score and to determine the effect of ticagrelor monotherapy versus DAPT in patients with or without high bleeding risk (HBR).

Methods

A post hoc analysis of the GLOBAL LEADERS trial was performed to compare the predictive value of the ZON-HR cla

SUBMITTER: Woelders ECI 

PROVIDER: S-EPMC11781092 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature