Understanding neurocognitive recovery in older adults after total hip arthroplasty-neurocognitive assessment, blood biomarkers and patient experiences: a mixed-methods study.

ABSTRACT:

Objective

Delayed neurocognitive recovery, previously known as postoperative cognitive dysfunction, is a common complication affecting older adults after surgery. This study aims to address the knowledge gap in postoperative neurocognitive recovery by exploring the relationship between subjective experiences, performance-based measurements, and blood biomarkers.

Design

Mixed-methods study with a convergent parallel (QUAL+quan) design.

Setting and participants

The study reports results from 40 older adult patients (52.5% women; mean age 73, SD 6.7) scheduled for total hip arthroplasty at a hospital in Sweden.

Outcome measures

Neurocognitive performance was assessed using a standardised test battery, neuroinflammation through blood biomarker analysis and postoper

SUBMITTER: Amirpour A 

PROVIDER: S-EPMC11781142 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature