Predicting the risk of bone metastases in patients with newly diagnosed prostate cancer - Development and validation of a nomogram model.

ABSTRACT:

Objectives

The aim of this study was to develop and validate a nomogram model that predicts the risk of bone metastasis (BM) in a prostate cancer (PCa) population.

Methods

We retrospectively collected and analyzed the clinical data of patients with pathologic diagnosis of PCa from January 1, 2013 to December 31, 2022 in two hospitals in Yangzhou, China. Patients from the Affiliated Hospital of Yangzhou University were divided into a training set and patients from the Affiliated Clinical College of Traditional Chinese Medicine of Yangzhou University were divided into a validation set. Chi-square test, independent sample t-test, and logistic regression were used to screen key risk factors. Receiver operating characteristic (ROC) curves, c-index, calibration curves, and decisio

SUBMITTER: Xu W 

PROVIDER: S-EPMC11781626 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature