Carotid artery stenosis and ischemic cerebrovascular events after radiotherapy in patients with head and neck cancer.

ABSTRACT: Radiotherapy is the main treatment for patients with head and neck cancer (HNC) and is associated with an increased risk of ischemic cerebrovascular events (ICVE). The purpose of this cross-sectional study was to determine the incidence of ICVE and carotid artery stenosis (CAS) in patients with HNC who receive radiotherapy and the risk factors for CAS. We enrolled 907 patients with HNC who underwent radiotherapy between February 2011 and June 2022 and obtained information on their clinical and tumor characteristics and their treatment from the clinical records. Data on risk factors for atherosclerosis, medications used, and radiotherapy were also collected. The patients were followed through to the end of 2023 unless they died or were lost to follow-up. The overall incidence of ICVE was 1.

SUBMITTER: Taengsakul N 

PROVIDER: S-EPMC11781643 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature