Small Cell Lung Cancer with Dual Paraneoplastic Syndromes: A Case Report.

ABSTRACT:

Introduction

Paraneoplastic syndromes are common in cancers such as lung, breast, and ovarian cancers. Still, the dual paraneoplastic syndromes of ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) and raised pancreatic enzymes at the same time are rare. EAS is due to the production of ACTH by tumors other than the pituitary gland, which stimulates the hyperplasia of the adrenal cortex to secrete excessive corticosteroids, most commonly in lung cancer. Elevated pancreatic enzymes are associated with ectopic secretion from lung cancer. Clinically, some patients with small cell lung cancer (SCLC) have atypical early clinical manifestations and may present with paraneoplastic syndrome as the first symptom.

Case report

This article describes a case of a 45-year-old male p

SUBMITTER: Song J 

PROVIDER: S-EPMC11781813 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature