High-risk plaques in non-culprit lesions and clinical outcome after NSTEMI vs. STEMI.

ABSTRACT:

Aims

Complete non-culprit (NC) revascularisation may help reduce recurrent events after non-ST-segment elevation myocardial infarction (NSTEMI), especially if NC lesions would harbour high-risk plaque (HRP) features similar to ST-segment elevation myocardial infarction (STEMI). This study aimed to assess differences in fractional flow reserve (FFR)-negative NC plaque morphology in patients presenting with NSTEMI vs. STEMI and assess the association of HRP morphology and clinical outcome.

Methods and results

In the prospective PECTUS-obs study, 438 patients presenting with myocardial infarction (MI) underwent optical coherence tomography (OCT) of all FFR-negative intermediate NC lesions. The primary endpoint was the occurrence of major adverse cardiovascular events (MACE, com

SUBMITTER: Volleberg RHJA 

PROVIDER: S-EPMC11781827 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature