Associations of psychotic symptom dimensions with clinical and developmental variables in twin and general clinical samples.

ABSTRACT:

Background

Positive, negative and disorganised psychotic symptom dimensions are associated with clinical and developmental variables, but differing definitions complicate interpretation. Additionally, some variables have had little investigation.

Aims

To investigate associations of psychotic symptom dimensions with clinical and developmental variables, and familial aggregation of symptom dimensions, in multiple samples employing the same definitions.

Method

We investigated associations between lifetime symptom dimensions and clinical and developmental variables in two twin and two general psychosis samples. Dimension symptom scores and most other variables were from the Operational Criteria Checklist. We used logistic regression in generalised linear mixed models for

SUBMITTER: Cardno AG 

PROVIDER: S-EPMC11781858 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature