A clinical decision model for failed adrenal vein sampling in primary aldosteronism.

ABSTRACT:

Objective

Primary aldosteronism (PA) is a common cause of secondary hypertension with unilateral and bilateral subtypes requiring different treatments. Adrenal vein sampling (AVS) is the gold standard for subtype differentiation but can be unsuccessful by challenging right adrenal vein anatomy. This study aimed to develop a clinical decision model using only measurements from the left adrenal vein (LAV) and peripheral blood (IVC) to differentiate between PA subtypes.

Methods

The retrospective cohort study included 54 PA patients who underwent bilaterally successful AVS. The main objective was to determine optimal cut-off values for the LAV/IVC index, using ROC analysis for subtype prediction. The predictive value of this index was assessed with the Area Under the Curve (AUC)

SUBMITTER: Ter Haar SNM 

PROVIDER: S-EPMC11782024 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature