Association between oxidative balance scores and peripheral artery disease in US adults: a cross-sectional study.

ABSTRACT:

Background

The Oxidative Balance Score (OBS) quantifies the overall oxidative stress burden, with higher scores indicating greater antioxidant (relative to prooxidant) activity. This study aimed to examine the association between peripheral arterial disease (PAD) and OBS.

Methods and materials

Data from the National Health and Nutrition Examination Survey (NHANES, 1999-2004) were analyzed for participants with ankle-brachial index (ABI) measurements. The total Oxidative Balance Score (OBS) comprised a lifestyle OBS (four lifestyle categories) and a dietary OBS (16 dietary factors). Logistic regression analyses evaluated associations between PAD and total OBS, lifestyle OBS, and dietary OBS. Restricted cubic spline (RCS) analyses assessed dose-response relationships between A

SUBMITTER: Zhou M 

PROVIDER: S-EPMC11782040 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature