Prevalence and clinical correlates of <i>Gardnerella</i> spp., <i>Fannyhessea vaginae</i>, <i>Lactobacillus crispatus</i> and <i>L. iners</i> in pregnant women in Bukavu, Democratic Republic of the Congo.

ABSTRACT:

Background

Gardnerella is a key pathogen in bacterial vaginosis (BV), but the role of the different Gardnerella species remains unclear. We investigated the role of four Gardnerella species, as well as Fannyhessea vaginae, Lactobacillus crispatus and L. iners in BV.

Methods

From 331 pregnant women from the Democratic Republic of the Congo, BV was diagnosed using Nugent scoring and a cervicovaginal lavage was used to quantify G. leopoldii, G. piotii, G. swidsinskii, G. vaginalis, F. vaginae, L. crispatus and L. iners by qPCR. Univariate associations between these species and clinical outcomes were assessed. A logistic regression model and ROC curves were calculated to determine the best diagnostic marker fo

SUBMITTER: Himschoot L 

PROVIDER: S-EPMC11782042 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature