High rate of persistent HPV detection after diagnostic cervical excision in older screen-positive women.

ABSTRACT:

Introduction

Diagnostic work-up of older women with a positive cervical cancer screening test is often challenging due to incomplete visualization of the transformation zone. To reduce the risk of missing disease, a diagnostic cervical excision may be performed. However, little is known on treatment efficacy and post-treatment surveillance for older women. We aimed to investigate the proportion of women testing negative for human papillomavirus (HPV) following a diagnostic cervical excision due to an abnormal screening test.

Material and methods

We conducted a prospective cohort study on women aged ≥45 years who were referred for colposcopy due to an abnormal screening test between March 2019 and June 2021. All women had incomplete visualization of the transformation zone an

SUBMITTER: Gustafson LW 

PROVIDER: S-EPMC11782055 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature