Effectiveness and Safety of Pulsed Field Ablation in Patients With Atrial Fibrillation.

ABSTRACT:

Background

As a competitive nonthermal energy technique used in atrial fibrillation (AF), the effectiveness and safety of pulsed field ablation (PFA) has remained uncertain.

Objectives

The authors meta-analysis aimed to investigate the effectiveness and safety of PFA in treating AF patients and compare its outcomes with conventional thermal ablation.

Methods

The PubMed, Embase, and Cochrane Library databases were systematically searched until January 2024 for relevant studies investigating the use of PFA for AF. A fixed-effects model was used for pooled analysis if the I² value was <50%; otherwise, a random-effects model was applied.

Results

A total of 46 studies were included in this analysis. The single-arm meta-analysis of 40 studies showed an acu

SUBMITTER: Li R 

PROVIDER: S-EPMC11782097 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature