Short-Term Risk of Cardiovascular Events in People Newly Diagnosed With Gout.

ABSTRACT:

Objective

To investigate the temporal association between the first diagnosis of gout and cardiovascular events in the short term.

Methods

We performed a self-controlled case series analysis and a cohort study using data from linked primary care, hospitalization, and mortality records from the United Kingdom's Clinical Practice Research Database-GOLD. We included individuals with a new diagnosis of gout either in the primary care or secondary care between January 1, 1997 and December 31, 2020. The first consultation at which gout was diagnosed was the exposure of interest. The main outcome consisted of cardiovascular events (ie, a composite of fatal and nonfatal myocardial infarction, ischemic or hemorrhagic stroke, and transient ischemic attack).

Results

The 4,398 pa

SUBMITTER: Cipolletta E 

PROVIDER: S-EPMC11782110 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature