Phylodynamic reconstruction of major chicken infectious anemia virus clades epidemiology, dispersal, and evolution.

ABSTRACT:

Introduction

Immunosuppressive diseases, such as chicken infectious anemia virus (CIAV), pose a major threat to livestock farming due to reduced disease resistance, poor vaccine response, and overall poor productivity. CIAV, recognized globally for decades, shows a significant genetic diversity, but its implications remain underexplored.

Methods

This study analyzed over 1,000 VP1 sequences and examined CIAV's epidemiology, evolution, and spread with various phylodynamic and phylogeographic approaches.

Results

Findings suggest that CIAV likely originated in Japan in the early 20th century, followed by worldwide diversification in two main clades. Both clades exhibited no significant competition and similar global patterns, characterized by a progressive increase until

SUBMITTER: Franzo G 

PROVIDER: S-EPMC11782247 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature