Gonadal miRNomes and transcriptomes in infected fish reveal sexually dimorphic patterns of the immune response.

ABSTRACT: Fish disease outbreaks caused by bacterial burdens are responsible for decreasing productivity in aquaculture. Unraveling the molecular mechanisms activated in the gonads after infections is pivotal for enhancing husbandry techniques in fish farms, ensuring disease management, and selecting the most resilience phenotype. The present study, with an important commercial species the European sea bass (Dicentrarchus labrax), an important commercial species in Europe, examined changes in the miRNome and transcriptome 48 h after an intraperitoneal infection with Vibrio anguillarum. The findings indicate that following infection, testes exhibited more pronounced alterations in both the miRNome and transcriptome. Specifically, males showed approximately 26% more differentially expressed genes in t

SUBMITTER: van Gelderen TA 

PROVIDER: S-EPMC11782434 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature