Multicenter and inter-software evaluation of ablative margins after thermal ablation of colorectal liver metastases.

ABSTRACT:

Purpose

To assess the association between minimal ablative margin (MAM) and local tumor progression (LTP) following CT-guided thermal ablation of colorectal liver metastases (CRLM) in a multicenter cohort and across two confirmation software.

Materials and methods

This multicenter retrospective study included patients who underwent CT-guided radiofrequency or microwave ablation for CRLM between 2009 and 2021 in three institutions. Three-dimensional (3D) MAM was retrospectively assessed using dedicated ablation confirmation software by automatic non-rigid (Ablation-fit) or semi-automatic rigid co-registration (SAFIR) of intraprocedural pre- and post-ablation contrast-enhanced CT scans by two independent reader teams blinded to patient outcomes. LTP was assessed on a per-tumor

SUBMITTER: Laimer G 

PROVIDER: S-EPMC11782453 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature