Proton-free induction decay MRSI at 7 T in the human brain using an egg-shaped modified rosette K-space trajectory.

ABSTRACT:

Purpose

Proton (¹H)-MRSI via spatial-spectral encoding poses high demands on gradient hardware at ultra-high fields and high-resolutions. Rosette trajectories help alleviate these problems, but at reduced SNR-efficiency because of their k-space densities not matching any desired k-space filter. We propose modified rosette trajectories, which more closely match a Hamming filter, and thereby improve SNR performance while still staying within gradient hardware limitations and without prolonging scan time.

Methods

Analytical and synthetic simulations were validated with phantom and in vivo measurements at 7 T. The rosette and modified rosette trajectories were measured in five healthy volunteers in 6 min in a 2D slice in the brain. An elliptical phase-encoding sequenc

SUBMITTER: Blomer S 

PROVIDER: S-EPMC11782714 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature