Reproducibility of liver ADC measurements using first moment optimized diffusion imaging.

ABSTRACT:

Purpose

Cardiac-induced liver motion can bias liver ADC measurements and compromise reproducibility. The purpose of this work was to enable motion-robust DWI on multiple MR scanners and assess reproducibility of the resulting liver ADC measurements.

Methods

First moment-optimized diffusion imaging (MODI) was implemented on three MR scanners with various gradient performances and field strengths. MODI-DWI and conventional Stejskal-Tanner monopolar (MONO) DWI were acquired in eight (N = 8) healthy volunteers on each scanner, and DWI repetitions were combined using three different averaging methods. For each combination of scanner, acquisition, and averaging method, ADC measurements from each liver segment were collected. Systematic differences in ADC values between scanners an

SUBMITTER: Allen TJ 

PROVIDER: S-EPMC11782722 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature