3D distortion-free, reduced FOV diffusion-prepared gradient echo at 3 T.

ABSTRACT:

Purpose

To develop a 3D distortion-free reduced-FOV diffusion-prepared gradient-echo sequence and demonstrate its application in vivo for diffusion imaging of the spinal cord in healthy volunteers.

Methods

A 3D multi-shot reduced-FOV diffusion-prepared gradient-echo acquisition is achieved using a slice-selective tip-down pulse in the phase-encoding direction in the diffusion preparation, combined with magnitude stabilizers, centric k-space encoding, and 2D phase navigators to correct for intershot phase errors. The accuracy of the ADC values obtained using the proposed approach was evaluated in a diffusion phantom and compared to the tabulated reference ADC values and to the ADC values obtained using a standard spin echo diffusion-weighted single-shot EPI sequence (DW-SS-EP

SUBMITTER: McElroy S 

PROVIDER: S-EPMC11782725 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature