Romer-EPTI: Rotating-view motion-robust super-resolution EPTI for SNR-efficient distortion-free in-vivo mesoscale diffusion MRI and microstructure imaging.

ABSTRACT:

Purpose

To overcome the major challenges in diffusion MRI (dMRI) acquisition, including limited SNR, distortion/blurring, and susceptibility to motion artifacts.

Theory and methods

A novel Romer-EPTI technique is developed to achieve SNR-efficient acquisition while providing distortion-free imaging, minimal spatial blurring, high motion robustness, and simultaneous multi-TE imaging. It introduces a ROtating-view Motion-robust supEr-Resolution technique (Romer) combined with a distortion/blurring-free Echo Planar Time-resolved Imaging (EPTI) readout. Romer enhances SNR through simultaneous multi-thick-slice acquisition with rotating-view encoding, while providing high motion-robustness via a high-fidelity, motion-aware super-resolution reconstruction. Instead of EPI, the in-p

SUBMITTER: Dong Z 

PROVIDER: S-EPMC11782731 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature