Changes in kidney function after adrenalectomy in patients with primary aldosteronism.

ABSTRACT:

Objectives

A decrease in the estimated glomerular filtration rate (eGFR) is occasionally observed in patients with primary aldosteronism (PA) after adrenalectomy. Patients may misunderstand that the surgical stress of adrenalectomy can result in kidney dysfunction. However, this finding is considered due to postoperative manifestations of kidney dysfunction that are masked preoperatively by excess aldosterone. To evaluate kidney dysfunction unmasked by adrenalectomy, we investigated changes in the eGFR after adrenalectomy according to the clinically assessable indication of "a certain drop in eGFR" as defined by the 2012 Kidney Disease Improving Global Outcomes clinical practice guideline.

Methods

This study included 54 patients with PA who underwent unilateral adrenalectomy

SUBMITTER: Tomiie Y 

PROVIDER: S-EPMC11782942 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature