In Silico Evaluation of Algorithm-Based Clinical Decision Support Systems: Protocol for a Scoping Review.

ABSTRACT:

Background

Integrating algorithm-based clinical decision support (CDS) systems poses significant challenges in evaluating their actual clinical value. Such CDS systems are traditionally assessed via controlled but resource-intensive clinical trials.

Objective

This paper presents a review protocol for preimplementation in silico evaluation methods to enable broadened impact analysis under simulated environments before clinical trials.

Methods

We propose a scoping review protocol that follows an enhanced Arksey and O'Malley framework and PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines to investigate the scope and research gaps in the in silico evaluation of algorithm-based CDS models-specifically C

SUBMITTER: Dorosan M 

PROVIDER: S-EPMC11783031 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature