Research Trends and Dynamics in Single-cell RNA Sequencing for Musculoskeletal Diseases: A Scientometric and Visualization Study.

ABSTRACT: Background: Worldwide, approximately 1.7 billion people are afflicted with musculoskeletal (MSK) diseases, posing significant health challenges. The introduction of single-cell RNA sequencing (scRNA-seq) technology provides novel insights and approaches to comprehend the onset, progression, and treatment of MSK diseases. Nevertheless, there is a remarkable lack of analytical and descriptive studies regarding the trajectory, essential research directions, current research situation, pivotal research focuses, and upcoming perspectives. Therefore, the aim of this research is to present a comprehensive overview of the advancements made in scRNA-seq for MSK disorders over the past 15 years. Methods: It utilizes a robust dataset derived from the Web of Science Core Collection, enco

SUBMITTER: Cao S 

PROVIDER: S-EPMC11783068 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature