Quo vadis autoimmune hepatitis? - Summary of the 5^th international autoimmune hepatitis group research workshop 2024.

ABSTRACT: Autoimmune hepatitis (AIH) is a rare chronic liver disease with an increasing incidence in many countries. Chronic autoimmune responses against the liver can cause hepatic and extrahepatic symptoms, decreased quality of life and reduced liver transplant-free survival if inadequately treated. Although standard treatment with corticosteroids and thiopurines improves the life expectancy of patients with AIH, remission rates and tolerability are generally overestimated and the development of alternative first-line and salvage therapies has been disappointingly slow compared to in rheumatological diseases or inflammatory bowel disease. Other gaps include the lack of disease-specific diagnostic markers for AIH. Similarly, the new entity of drug-induced autoimmune-like hepatitis underscores the n

SUBMITTER: Engel B 

PROVIDER: S-EPMC11783120 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature