Cohort retention in a pandemic response study: lessons from the SARS-CoV2 Immunity & Reinfection Evaluation (SIREN) study.

ABSTRACT:

Background

SIREN is a healthcare worker cohort study aiming to determine COVID-19 incidence, duration of immunity and vaccine effectiveness across 135 NHS organisations in four UK nations. Conducting an intensive prospective cohort study during a pandemic was challenging. We designed an evolving retention programme, informed by emerging evidence on best practice. This included applying a multifactorial approach, and considering strategies for barrier reduction, community building, follow-up, and tracing. We utilised participant engagement tools underpinned by our Participant Involvement Panel (PIP) and here we evaluate cohort retention over time and identify learnings.

Methods

A mixed method evaluation of cohort retention in 12 and 24-month follow-up (June 2020 - March 2023)

SUBMITTER: Howells A 

PROVIDER: S-EPMC11783804 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature