Development and validation of a nomogram for predicting perioperative transfusion in children undergoing cardiac surgery with CPB.

ABSTRACT:

Background

Timely recognition of perioperative red blood cell transfusion (PRT) risk is crucial for developing personalized blood management strategies in pediatric patients. In this study, we sought to construct a prediction model for PRT risk in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass (CPB).

Methods

From September 2014 to December 2021, 23,884 pediatric patients under the age of 14 were randomly divided into training and testing cohorts at a 7:3 ratio. Variable selection was performed using univariate logistic regression and least absolute shrinkage and selection operator (LASSO) regression. Multivariate logistic regression was then used to identify predictors, and a nomogram was developed to predict PRT risk. The model's performance was e

SUBMITTER: Wang W 

PROVIDER: S-EPMC11783815 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature