Drug-related macular edema: a real-world FDA Adverse Event Reporting System database study.

ABSTRACT:

Purpose

This study aims to assess the risks associated with drug-induced macular edema and to examine the epidemiological characteristics of this condition.

Methods

This study analyzed data from the U.S. Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database from January 2004 to June 2024 to conduct a disproportionality analysis identifying drugs with positive signals of drug-induced ME. Additionally, the onset time of ME associated with these drugs was examined.

Results

In the FAERS database, a total of 490 drugs were reported to pose a risk of drug-induced ME. Disproportional analysis and screening further identified 8 drugs that significantly increased this risk. Among these, one is ophthalmic drugs, including Latanoprost (ROR = 5.51), a

SUBMITTER: Li X 

PROVIDER: S-EPMC11783817 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature