Periodontal diseases in Down syndrome during childhood: a scoping review.

ABSTRACT:

Background

Down syndrome (DS) is a genetic condition that involves the deregulation of immune function and is characterized by a proinflammatory phenotype leading to an impaired response to infections. Periodontitis is a highly prevalent chronic inflammatory disease. It has been shown that adults and teenagers with DS are more susceptible to this disease, but a similar correlation in DS children remains elusive. This systematic scoping review aims to address this knowledge gap by examining periodontitis in DS children, with a secondary objective of elucidating the underlying mechanisms involved.

Methods

Our primary search was conducted via the PubMed/MEDLINE database and Google Scholar, covering the period from 1951-July 1st, 2024. Primary studies written in English or Frenc

SUBMITTER: Vergier V 

PROVIDER: S-EPMC11783834 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature