Longitudinal association between hemoglobin and lung function with insights into the incidence of airflow obstruction: an observational study.

ABSTRACT:

Background/aims

Evidence regarding the long-term association between hemoglobin (Hb) levels and lung function in individuals from the general population is scarce. This study aimed to determine the longitudinal association between Hb levels and lung function in a community-based population cohort in South Korea.

Methods

We used linear mixed regression analysis to evaluate the longitudinal associations between Hb levels and lung function parameters, including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV₁), and FEV₁/FVC. Additionally, we used a generalized estimating equation to calculate the odds ratio (OR) of airflow obstruction (AO) according to the Hb level.

Results

Over an 8-year biennial follow-up of 4,468 individuals (me

SUBMITTER: Kim J 

PROVIDER: S-EPMC11783840 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature