Timing of high-definition transcranial direct current stimulation to the nondominant primary motor cortex fails to modulate cortical hemodynamic activity and improve motor sequence learning.

ABSTRACT:

Background

The relative timing of transcranial direct current stimulation (tDCS) and motor practice holds potential importance in modulating cortical activity and facilitating behavioral performance.

Method

A single-blind, randomized, cross-over experiment was conducted. Twenty healthy participants engaged in a sequential finger-tapping task with their left hand. High-definition anodal tDCS (1 mA, 20 min) was administered over the right primary motor cortex (M1) either during (concurrent-tDCS) or before the motor practice (prior-tDCS). A sham tDCS condition was also employed. The three tDCS conditions were separated by one-week intervals. Cortical hemodynamic activity in the prefrontal cortex (PFC), supplementary motor area (SMA), and M1 measured by functional near-infrared

SUBMITTER: Jin M 

PROVIDER: S-EPMC11783929 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature