Tracing <i>Staphylococcus capitis</i> and <i>Staphylococcus epidermidis</i> strains causing septicemia in extremely preterm infants to the skin, mouth, and gut microbiota.

ABSTRACT: Coagulase-negative staphylococci (CoNS) comprise about 50 species, some of which cause septicemia in preterm neonates. CoNS establish early on the skin and in the oral and gut microbiota, from where they may spread to the bloodstream. The colonization pattern preceding septicemia is not well-defined. Forty-two extremely preterm neonates (≤28 + 0 gestational weeks) were followed from birth to 2 months with regular sampling and culturing of the skin and oral and gut microbiota. Blood samples were drawn upon clinical suspicion of septicemia and cultured. CoNS species were identified using matrix-assisted laser-desorption ionization time of flight mass spectrometry (MALDI-TOF). Random amplified polymorphic DNA was used for strain typing, and strains were characterized regarding biofilm product

SUBMITTER: Nowrouzian FL 

PROVIDER: S-EPMC11784025 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature