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Efficacy and safety of anti-thrombotic therapy after surgical mitral valve repair: a scoping review.


ABSTRACT:

Background

Mitral valve repair (MVr) is the gold standard treatment for degenerative mitral regurgitation, yet there is ongoing controversy regarding optimal anti-thrombotic therapy post-MVr. This scoping review aimed to summarise current evidence on the safety and efficacy of anti-thrombotic therapy after MVr, identify knowledge gaps and propose a future study design.

Methods

We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Clinicaltrials.gov, the WHO International Clinical Trials Registry Platform and bibliographies of included trials, guidelines and other reviews from inception to 17 September 2024. Randomised controlled trials (RCT) and cohort and case-control studies assessing any anti-thrombotic therapy with any outcomes after MVr were inclu

SUBMITTER: Babadagli HE 

PROVIDER: S-EPMC11784107 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature