Regulation mechanism of the long-chain <i>n</i>-alkane monooxygenase gene <i>almA</i> in <i>Acinetobacter venetianus</i> RAG-1.

ABSTRACT: As toxic pollutants, n-alkanes are pervasively distributed in most environmental matrices. Although the alkane monooxygenase AlmA plays a critical role in the metabolic pathway of solid long-chain n-alkanes (≥C₂₀) that are extremely difficult to degrade, the mechanism regulating this process remains unclear. Here, we characterized the function of AlmA in Acinetobacter venetianus RAG-1, which was mainly involved in the degradation of long-chain n-alkanes (C₂₆-C₃₈), among which, n-C₃₂ induced the almA promoter activity most. APR1 (AlmA Positive Regulator) that it is an AraC/XylS-type transcription regulator, a potential transcriptional regulator of almA, was screened by DNA-pull

SUBMITTER: Chen S 

PROVIDER: S-EPMC11784139 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature