Genomic and metabolic characterization of <i>Trueperella pyogenes</i> isolated from domestic and wild animals.

ABSTRACT: Trueperella pyogenes is an important bacterial pathogen implicated in infections such as mastitis, metritis, pneumonia, and liver abscesses in both domestic and wild animals, as well as endocarditis and prosthetic joint infections in humans. Understanding the genomic and metabolic features that enable T. pyogenes to colonize different anatomical sites within a host and its inter-kingdom transmission and survival is important for the effective control of this pathogen. We employed whole-genome sequencing, phenotype microarrays, and antimicrobial susceptibility testing to identify genomic, metabolic and phenotypic features, and antimicrobial resistance (AMR) genes in T. pyogenes recovered from different livestock, companion, and wildlife animals. For comparative genomic

SUBMITTER: Magossi G 

PROVIDER: S-EPMC11784230 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature