Emergence of terbinafine-resistant <i>Trichophyton indotineae</i> in Ontario, Canada, 2014-2023.

ABSTRACT: Trichophyton indotineae is an emerging fungal pathogen capable of causing extensive recalcitrant dermatophytosis exacerbated by frequently retained terbinafine resistance. Cases of dermatophytosis due to T. indotineae have increased dramatically in India in recent years. Other countries have reported imported infection cases, causing public health concerns over the potential global spread of this drug-resistant pathogen. We describe T. indotineae from 47 clinical cases in Ontario, Canada, from 2014 to 2023, based on 50 isolates received by the provincial public health laboratory. Although detected in Ontario as early as 2014, cases increased sharply in 2022-2023. The majority of cases were found in 20 to 64-year-olds (83.0%). Cases from 2022 to 2023 were noted in only

SUBMITTER: McTaggart LR 

PROVIDER: S-EPMC11784349 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature