Multifunctional bending magnet beamline with a capillary optic for X-ray fluorescence studies of metals in tissue sections.

ABSTRACT: Scanning fluorescence X-ray microscopy lets one non-destructively and quantitatively map the distribution of most biologically-important metals in cells and tissues. For studies on large-scale tissues and organs, a spatial resolution of several micrometers is often sufficient; in this case, bending magnets at synchrotron light sources provide abundant X-ray flux. We describe here the use of bending magnet beamline 8-BM-B at the Advanced Photon Source (APS) with two distinct microscopy stations: a pre-existing one with Kirkpatrick-Baez (KB) mirror optics for slightly higher throughput and the ability to accommodate samples tens of centimeters across, and a new prototype station with an axially-symmetric, single-bounce, capillary optic with slightly less flux, but slightly higher fluence (wh

SUBMITTER: Roter B 

PROVIDER: S-EPMC11785041 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature