Comparative Patterns of Variation on the X Chromosome and Autosomes: The Role of the Breeding Sex Ratio.

ABSTRACT: In many populations, unequal numbers of females and males reproduce each generation. This imbalance in the breeding sex ratio (BSR) shapes patterns of genetic variation on the sex chromosomes and the autosomes in distinct ways. Despite recognition of this phenomenon, effects of the BSR on some aspects of variation remain unclear, especially for populations with non-equilibrium demographic histories. To address this gap in the field, we used coalescent simulations to examine relative patterns of variation at X-linked loci and autosomal loci in populations spanning the range of BSR with historical changes in population size. Shifts in BSR away from 1:1 reduce nucleotide diversity and the number of unique haplotypes and increase linkage disequilibrium and the frequency of the most common hapl

SUBMITTER: Spurley WJ 

PROVIDER: S-EPMC11785124 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature