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Pharmacologic Management of Obesity in Neuro-Oncology: A Case Report.


ABSTRACT:

Introduction

Brain tumors are the most common solid tumors in pediatric oncology. Advances in the treatment of childhood brain tumors have led to increased survival; however, treatment-related morbidity remains high. The risk of developing overweight/obesity or significant weight gain is commonly observed in children with a brain tumor often due to hypothalamic damage as a result of radiation therapy, surgery, or the tumor itself. This may be accompanied by endocrinopathies such as diabetes insipidus and central precocious puberty in survivors of a childhood brain tumor. Lifestyle intervention strategies are often ineffective in preventing and managing obesity. Patients have difficulty with adherence to dietary interventions due to prolonged exposure to high-dose steroids, compromi

SUBMITTER: Lardieri A 

PROVIDER: S-EPMC11785398 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature