Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours.

ABSTRACT:

Introduction

Gut microbiome-derived nanoparticles, known as bacterial extracellular vesicles (bEVs), have garnered interest as promising tools for studying the link between the gut microbiome and human health. The diverse composition of bEVs, including their proteins, mRNAs, metabolites, and lipids, makes them useful for investigating diseases such as cancer. However, conventional approaches for studying gut microbiome composition alone may not be accurate in deciphering host-gut microbiome communication. In clinical microbiome research, there is a gap in the knowledge on the role of bEVs in solid tumor patients.

Objectives

Analyzing the functionality of bEVs using (meta)genomics and proteomics could highlight the unique aspects of host-gut microbiome interactions in solid t

SUBMITTER: Mishra S 

PROVIDER: S-EPMC11785572 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature