Identification of a transcription factor AoMsn2 of the Hog1 signaling pathway contributes to fungal growth, development and pathogenicity in Arthrobotrys oligospora.

ABSTRACT:

Introduction

Arthrobotrys oligospora has been utilized as a model strain to study the interaction between fungi and nematodes owing to its ability to capture nematodes by developing specialized traps. A previous study showed that high-osmolarity glycerol (Hog1) signaling regulates the osmoregulation and nematocidal activity of A. oligospora. However, the function of downstream transcription factors of the Hog1 signaling in the nematode-trapping (NT) fungi remains unclear.

Objective

This study aimed to investigate the functions and potential regulatory network of AoMsn2, a downstream transcription factor of the Hog1 signaling pathway in A. oligospora.

Methods

The function of AoMsn2 was characterized using targeted gene deletion, phenotypic experiments, real-time quanti

SUBMITTER: Liu Q 

PROVIDER: S-EPMC11785577 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature