Discordance between peritumoral and subareolar injections for mapping sentinel lymph nodes in the breast.

ABSTRACT:

Purpose

Sentinel node biopsy (SNB) is a common staging tool for breast cancer. Initially, peritumoral (PT) injections were used, however subareolar (SA) injections were later introduced to simplify the technique. Controversy remains regarding whether PT and SA injections map the same sentinel lymph nodes (SLNs). This study aimed to determine whether the regional location of breast SLNs differs when using PT versus SA injections using a large dataset from a single institution.

Methods

A total of 1035 patients who underwent breast SNB (PT injections: n = 858 and SA injections: n = 177) with lymphoscintigraphy and SPECT/CT were included. The identified SLN locations using SA injections were compared with those using PT injections. Differences in drainage proportions and odds ra

SUBMITTER: Situ J 

PROVIDER: S-EPMC11785644 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature