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Breast cancer recurrence in relation to mode of detection: implications on personalized surveillance.


ABSTRACT:

Purpose

The effectiveness of current follow-up guidelines after breast cancer treatment is uncertain. Tailored surveillance based on patient age and tumor characteristics may be more adequate. This study aimed to analyze the frequency of ipsilateral locoregional recurrences (LR) and second primary breast cancers (SP) detected outside of scheduled surveillance and to analyze risk factors associated with these events.

Methods

Patients with surgically treated early-stage breast cancer from the Malmö Diet and Cancer Study (MDCS), 1991-2014 (n = 1080), and the Västernorrland region, 2009-2018 (n = 1648), were included. Clinical and pathological information on the primary tumor and recurrences was retrieved from medical records. The mode of recurrence detection was defined as dete

SUBMITTER: Sartor H 

PROVIDER: S-EPMC11785654 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature