Investigating the relationship between cognitive impairment and brain white matter tracts using diffusion tensor imaging in patients with prolactinoma.

ABSTRACT:

Background

Cognitive impairment is known to occur in patients with prolactinoma, but the underlying mechanism is unclear.

Objective

To evaluate cognitive function in patients with prolactinoma and to investigate the basis of possible cognitive impairment in brain white matter changes using diffusion tensor imaging (DTI).

Methods

37 consecutive patients with prolactinoma and 37 healthy controls of similar age, sex, and education were enrolled in the study. Hormone levels were determined in all participants, comprehensive neuropsychological testing was performed, and DTI was used to reconstruct and evaluate white matter tracts.

Results

In patients with prolactinoma, short- and long-term visual and verbal memory, attention, concentration, and executive and languag

SUBMITTER: Duru M 

PROVIDER: S-EPMC11785683 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature