Accelerated symptom improvement in Parkinson's disease via remote internet-based optimization of deep brain stimulation therapy: a randomized controlled multicenter trial.

ABSTRACT:

Background

Deep brain stimulation (DBS) has emerged as an important therapeutic intervention for neurological and neuropsychiatric disorders. After initial programming, clinicians are tasked with fine-tuning DBS parameters through repeated in-person clinic visits. We aimed to evaluate whether DBS patients achieve clinical benefit more rapidly by incorporating remote internet-based adjustment (RIBA) of stimulation parameters into the continuum of care.

Methods

We conducted a randomized controlled multicenter study (ClinicalTrails.gov NCT05269862) involving patients scheduled for de novo implantation with a DBS System to treat Parkinson's Disease. Eligibility criteria included the ability to incorporate RIBA as part of routine follow-up care. Ninety-six patients were randomly

SUBMITTER: Gharabaghi A 

PROVIDER: S-EPMC11785990 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature